Platelet Riche Fibrin

The concept of PRF is based on the centrifugation of whole blood. At the end of the centrifugation, a fibrin clot is obtained containing platelets and a majority of white cells.

This fibrin clot called Platelet Rich Fibrin or PRF will progressively and constantly release growth factors or cytokines into the environment.

The expected objective of these growth factors is to accelerate mucosal and bone healing.

The expected objective of these growth factors is to accelerate mucosal and bone healing.
Numerous international publications are available and demonstrate the effectiveness of PRF in many indications: in oral surgery (implantology, bone grafts, periodontal surgery, extractions, etc.), in orthopedic, cosmetic and dermatological surgery.

The PRF is considered a healing biomaterial synthesizing in a single membrane all the parameters necessary for optimal healing: a fibrin matrix polymerized into a tetramolecular architecture, intrinsic incorporation of platelet and leukocyte cytokines into the fibrin mesh, platelets, leukocytes, and also some circulating stem cells.

However, although the cytokines trapped in the PRF and progressively released allow the acceleration of all cellular phenomena, the coherent and structured fibrin matrix necessarily remains the key element of all PRF-potentiated wound healing. This totally natural biomaterial appears to effectively accelerate physiological healing phenomena.

Sinus fillings, Implantology

Bone grafts, Periodontics

Cicatrisation, Extraction